Statements (76)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:protein
|
| gptkbp:associated_with |
angiogenesis
|
| gptkbp:function |
modulating cell-matrix interactions
|
| gptkbp:has_role |
inflammation
fibrosis tissue remodeling |
| https://www.w3.org/2000/01/rdf-schema#label |
SPARC family
|
| gptkbp:includes |
gptkb:osteonectin
gptkb:SPARC-like_protein_1 gptkb:SPARC_protein gptkb:BM-40 |
| gptkbp:involved_in |
wound healing
cell adhesion tumor progression |
| gptkbp:is_associated_with |
cell migration
metastasis ECM remodeling angiogenic processes |
| gptkbp:is_characterized_by |
modular structure
calcium-binding properties extracellular localization high glycine content |
| gptkbp:is_expressed_in |
various tissues
|
| gptkbp:is_found_in |
gptkb:fish
gptkb:amphibians gptkb:birds gptkb:mammals reptiles |
| gptkbp:is_involved_in |
gptkb:neurodegenerative_diseases
apoptosis cell cycle regulation cell differentiation cell proliferation cell signaling endocrinology genetic disorders immune response metabolic disorders metabolic processes signal transduction autoimmune diseases chronic diseases stem cell biology cancer biology embryogenesis infectious diseases cell survival developmental biology organogenesis neurobiology tissue repair aging processes cardiovascular biology neovascularization muscle biology matrix mineralization |
| gptkbp:is_regulated_by |
growth factors
cytokines |
| gptkbp:is_similar_to |
other protein families
|
| gptkbp:is_studied_in |
molecular biology
cell biology biomedical research pathology |
| gptkbp:orthologs |
other species
|
| gptkbp:related_to |
extracellular matrix
|
| gptkbp:bfsParent |
gptkb:SPARC64
gptkb:SPARC_M8 gptkb:SPARC_S13 gptkb:SPARC_S17 gptkb:SPARC_S8 gptkb:SPARC64_XLIV gptkb:SPARC64_XVI gptkb:Sun_Enterprise_series gptkb:SPARC_T-series gptkb:SPARC_V8 |
| gptkbp:bfsLayer |
6
|