|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:KMT3E
gptkb:ZMYND1
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:cancer
|
|
gptkbp:discoveredBy
|
gptkb:Hamamoto_et_al.
|
|
gptkbp:discoveredIn
|
2004
|
|
gptkbp:domain
|
gptkb:MYND_domain
SET domain
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000167601
64754
|
|
gptkbp:enzyme
|
lysine N-methyltransferase
|
|
gptkbp:expressedIn
|
ubiquitous, higher in cancer tissues
|
|
gptkbp:fullName
|
gptkb:SET_and_MYND_domain-containing_protein_3
|
|
gptkbp:function
|
histone methyltransferase
|
|
gptkbp:gene
|
gptkb:SMYD3
|
|
gptkbp:geneType
|
protein coding
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:16869
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
SMYD3
|
|
gptkbp:interactsWith
|
gptkb:RNA_polymerase_II
gptkb:HSP90
|
|
gptkbp:length
|
428 amino acids
|
|
gptkbp:locatedOnChromosome
|
1q44
|
|
gptkbp:methylates
|
gptkb:histone_H3K4
gptkb:histone_H4K5
|
|
gptkbp:mutationAssociatedWith
|
tumorigenesis
|
|
gptkbp:OMIM
|
608713
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Danio_rerio
gptkb:Mus_musculus
|
|
gptkbp:overexpressedIn
|
gptkb:cancer
colorectal cancer
prostate cancer
hepatocellular carcinoma
|
|
gptkbp:pathway
|
chromatin modification
epigenetic regulation
transcriptional regulation
|
|
gptkbp:regulates
|
transcription
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:target
|
small molecule inhibitors
|
|
gptkbp:UniProtID
|
gptkb:Q9H7B4
|
|
gptkbp:bfsParent
|
gptkb:chromosome_1q44
|
|
gptkbp:bfsLayer
|
7
|