|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:norepinephrine_transporter
gptkb:NET
gptkb:solute_carrier_family_6_member_2
|
|
gptkbp:associatedWith
|
gptkb:depression
gptkb:attention_deficit_hyperactivity_disorder
gptkb:orthostatic_intolerance
autonomic dysfunction
|
|
gptkbp:biologicalProcess
|
synaptic transmission
neurotransmitter reuptake
norepinephrine transmembrane transporter activity
|
|
gptkbp:cellularComponent
|
gptkb:plasma_membrane
|
|
gptkbp:discoveredBy
|
gptkb:Susan_Amara
|
|
gptkbp:encodes
|
gptkb:norepinephrine_transporter
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000140945
6530
|
|
gptkbp:expressedIn
|
gptkb:nervous_system
|
|
gptkbp:firstDescribed
|
1991
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:GOID
|
GO:0015874
|
|
gptkbp:HGNC_ID
|
11049
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
SLC6A2 (human)
|
|
gptkbp:length
|
617 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:16q12.2
gptkb:chromosome_16
|
|
gptkbp:mutationAssociatedWith
|
norepinephrine transporter deficiency
|
|
gptkbp:OMIM
|
163970
|
|
gptkbp:orthologInMouse
|
gptkb:Slc6a2
|
|
gptkbp:pathway
|
gptkb:synaptic_vesicle_cycle
neuroactive ligand-receptor interaction
noradrenaline neurotransmitter release cycle
|
|
gptkbp:PDB
|
6M0Y
|
|
gptkbp:product
|
gptkb:SLC6A2_protein
|
|
gptkbp:publicTransit
|
neurotransmitter transporter
|
|
gptkbp:RefSeq
|
NM_001043
|
|
gptkbp:target
|
gptkb:tricyclic_antidepressants
gptkb:desipramine
gptkb:atomoxetine
gptkb:reboxetine
gptkb:methylphenidate
cocaine
amphetamine
antidepressants
maprotiline
|
|
gptkbp:transportation
|
dopamine
norepinephrine
|
|
gptkbp:transporterFamily
|
gptkb:solute_carrier_family_6
|
|
gptkbp:UniProtID
|
P23975
|
|
gptkbp:bfsParent
|
gptkb:Slc6a2
|
|
gptkbp:bfsLayer
|
8
|