vasopressin receptor antagonists
GPTKB entity
Statements (25)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
|
| gptkbp:alsoKnownAs |
vaptans
|
| gptkbp:ATCCode |
C03XA01 (tolvaptan)
|
| gptkbp:contraindication |
anuria
hypovolemic hyponatremia |
| gptkbp:discoveredIn |
late 20th century
|
| gptkbp:example |
conivaptan
lixivaptan satavaptan tolvaptan |
| https://www.w3.org/2000/01/rdf-schema#label |
vasopressin receptor antagonists
|
| gptkbp:mechanismOfAction |
block vasopressin receptors
|
| gptkbp:notable_drug |
conivaptan
tolvaptan |
| gptkbp:regulates |
water excretion
|
| gptkbp:routeOfAdministration |
oral
intravenous |
| gptkbp:sideEffect |
thirst
polyuria hypernatremia |
| gptkbp:target |
vasopressin V1a receptor
vasopressin V2 receptor |
| gptkbp:usedFor |
treatment of hyponatremia
|
| gptkbp:bfsParent |
gptkb:SIADH
|
| gptkbp:bfsLayer |
6
|