|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:PSF
gptkb:Polypyrimidine_tract-binding_protein-associated-splicing_factor
|
|
gptkbp:associatedWith
|
amyotrophic lateral sclerosis
frontotemporal dementia
|
|
gptkbp:discoveredBy
|
1993
|
|
gptkbp:domain
|
RNA recognition motif
coiled-coil domain
|
|
gptkbp:encodedBy
|
gptkb:SFPQ_gene
|
|
gptkbp:Entrez_Gene_ID
|
6421
ENSG00000164105
|
|
gptkbp:expressedIn
|
gptkb:kidney
gptkb:testis
brain
heart
liver
|
|
gptkbp:formsComplexWith
|
gptkb:PSPC1
NONO
|
|
gptkbp:fullName
|
gptkb:Splicing_factor,_proline-_and_glutamine-rich
|
|
gptkbp:function
|
DNA repair
RNA splicing
RNA binding
transcription regulation
DNA binding
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:GOProcess
|
regulation of transcription, DNA-templated
double-strand break repair
mRNA processing
|
|
gptkbp:interactsWith
|
gptkb:RNA_polymerase_II
gptkb:FUS
gptkb:TAF15
gptkb:MATR3
gptkb:U2AF65
|
|
gptkbp:locatedIn
|
gptkb:nucleus
|
|
gptkbp:locatedOnChromosome
|
1p34.3
|
|
gptkbp:molecularWeight
|
76 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Drosophila_melanogaster
|
|
gptkbp:PDB
|
4WII
4WIJ
|
|
gptkbp:postTranslationalModification
|
phosphorylation
sumoylation
|
|
gptkbp:subcellularLocation
|
gptkb:nuclear_paraspeckles
|
|
gptkbp:UniProtID
|
P23246
|
|
gptkbp:bfsParent
|
gptkb:FUS_protein
|
|
gptkbp:bfsLayer
|
6
|
|
http://www.w3.org/2000/01/rdf-schema#label
|
SFPQ
|