Statements (70)
Predicate | Object |
---|---|
gptkbp:instance_of |
gptkb:drug
|
gptkbp:bfsLayer |
4
|
gptkbp:bfsParent |
gptkb:rifampin
gptkb:rifampicin |
gptkbp:activities |
inhibits RNA synthesis
|
gptkbp:brand |
gptkb:Rifampin
|
gptkbp:clinical_trial |
combination therapy
|
gptkbp:contraindication |
liver disease
hypersensitivity to rifampicin |
gptkbp:discovered_by |
1950s
|
gptkbp:dosage_form |
oral
150 mg 300 mg |
gptkbp:excretion |
bile
|
gptkbp:formulation |
gptkb:beer
gptkb:product gptkb:tablet |
https://www.w3.org/2000/01/rdf-schema#label |
Rimactane
|
gptkbp:ingredients |
C43 H58 N4 O12
Rifampicin |
gptkbp:interacts_with |
gptkb:warfarin
oral contraceptives |
gptkbp:is_atype_of |
J04 A B02
|
gptkbp:is_used_for |
tuberculosis
|
gptkbp:legal_issue |
prescription only
|
gptkbp:manager |
oral
|
gptkbp:metabolism |
liver
|
gptkbp:side_effect |
gptkb:historical_event
gptkb:fandom gptkb:Insurance_Company dizziness headache nausea allergic reactions fever liver failure vomiting confusion seizures urticaria gastrointestinal disturbances rash hearing loss insomnia sepsis chills peripheral neuropathy sweating anaphylaxis thrombocytopenia acute kidney injury hypotension cardiac arrhythmias hepatotoxicity psychosis gout flu-like symptoms nephrotoxicity thromboembolism angioedema visual disturbances pneumonitis suicidal ideation pulmonary toxicity rhabdomyolysis hyperuricemia cerebral edema orange discoloration of bodily fluids |
gptkbp:targets |
gptkb:Mycobacterium_tuberculosis
|
gptkbp:traded_on |
gptkb:Rifadin
|