Statements (66)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:drug
|
| gptkbp:bfsLayer |
5
|
| gptkbp:bfsParent |
gptkb:Rifadin
gptkb:Rimactane gptkb:rifamycins gptkb:Mavyret |
| gptkbp:activities |
inhibits RNA synthesis
|
| gptkbp:affects |
bacterial RNA polymerase
|
| gptkbp:appointed_by |
oral tablet
intravenous injection |
| gptkbp:approves |
gptkb:1966
|
| gptkbp:brand |
gptkb:Rifadin
gptkb:Rimactane |
| gptkbp:can_be_used_with |
gptkb:ethambutol
gptkb:isoniazid gptkb:pyrazinamide |
| gptkbp:category |
Category C
|
| gptkbp:contraindication |
hypersensitivity to rifampin
|
| gptkbp:developed_by |
prevention of meningococcal disease
treatment of leprosy Danish pharmaceutical company |
| gptkbp:excretion |
urine
bile |
| https://www.w3.org/2000/01/rdf-schema#label |
Rifampin
|
| gptkbp:ingredients |
C21 H19 N3 O4
|
| gptkbp:interacts_with |
gptkb:warfarin
oral contraceptives |
| gptkbp:is_atype_of |
J04 A B02
|
| gptkbp:is_used_for |
tuberculosis
bacterial infections |
| gptkbp:lifespan |
2 to 5 hours
|
| gptkbp:side_effect |
gptkb:fandom
dizziness fatigue headache nausea abdominal pain fever jaundice vomiting urticaria gastrointestinal disturbances rash hearing loss insomnia chills peripheral neuropathy sweating severe allergic reactions hemolytic anemia thrombocytopenia acute kidney injury hepatotoxicity anorexia flu-like symptoms thrombotic thrombocytopenic purpura visual disturbances acute liver failure arthralgia myalgia hyperuricemia toxic epidermal necrolysis Stevens-Johnson syndrome orange discoloration of bodily fluids |
| gptkbp:type_of |
13292-46-1
|
| gptkbp:water_resistance |
mutations in rpo B gene
|