Ribonucleoside-diphosphate reductase large subunit
GPTKB entity
Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:biologicalProcess |
cell cycle
DNA synthesis oxidoreductase activity |
| gptkbp:cofactor |
iron
manganese |
| gptkbp:enzymeCommissionNumber |
EC 1.17.4.1
|
| gptkbp:foundIn |
gptkb:Bacteria
eukaryotes |
| gptkbp:function |
catalyzes reduction of ribonucleotides to deoxyribonucleotides
|
| gptkbp:gene |
nrdA (in E. coli)
|
| gptkbp:GO_term |
gptkb:GO:0004748
|
| https://www.w3.org/2000/01/rdf-schema#label |
Ribonucleoside-diphosphate reductase large subunit
|
| gptkbp:inhibitedBy |
gptkb:hydroxyurea
|
| gptkbp:part_of |
gptkb:ribonucleotide_reductase_complex
|
| gptkbp:PDB |
1RIB (E. coli)
|
| gptkbp:presentIn |
gptkb:cytoplasm
mitochondria (in eukaryotes) |
| gptkbp:requires |
DNA replication
|
| gptkbp:structure |
forms homodimer or heterodimer with small subunit
|
| gptkbp:UniProtID |
P00452 (E. coli)
|
| gptkbp:bfsParent |
gptkb:RRM1
|
| gptkbp:bfsLayer |
7
|