Statements (50)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
free radical |
| gptkbp:abbreviation |
gptkb:ROS
|
| gptkbp:associatedWith |
gptkb:cancer
neurodegenerative diseases cardiovascular diseases inflammatory diseases |
| gptkbp:cause |
cell death
DNA damage lipid peroxidation protein oxidation |
| gptkbp:decreasedIn |
antioxidant therapy
|
| gptkbp:discoveredIn |
20th century
|
| gptkbp:effect |
signal transduction
gene expression enzyme activity redox homeostasis |
| gptkbp:hasComponent |
oxygen
|
| gptkbp:hasType |
gptkb:superoxide_anion
hydrogen peroxide ozone hydroxyl radical singlet oxygen peroxyl radical |
| https://www.w3.org/2000/01/rdf-schema#label |
Reactive Oxygen Species
|
| gptkbp:improves |
radiation therapy
UV radiation pollutants pathogen infection |
| gptkbp:measures |
gptkb:electron_spin_resonance
fluorescent probes chemiluminescence |
| gptkbp:neutralizedBy |
gptkb:superoxide_dismutase
antioxidants catalase glutathione peroxidase |
| gptkbp:producedBy |
gptkb:NADPH_oxidase
inflammation mitochondria peroxisomes |
| gptkbp:role |
apoptosis
aging cell signaling immune response oxidative stress |
| gptkbp:studiedIn |
gptkb:medicine
biochemistry cell biology |
| gptkbp:bfsParent |
gptkb:Reactive_Nitrogen_Species
|
| gptkbp:bfsLayer |
8
|