|
gptkbp:instanceOf
|
gptkb:protein
gptkb:enzyme
|
|
gptkbp:alternativeSplicing
|
no
|
|
gptkbp:associatedWith
|
cancer progression
metastasis
|
|
gptkbp:discoveredIn
|
1990s
|
|
gptkbp:encodedBy
|
gptkb:RALB_gene
|
|
gptkbp:form
|
GTP-bound
|
|
gptkbp:function
|
signal transduction
GTP binding
GTPase activity
|
|
gptkbp:gene
|
gptkb:RALB
|
|
gptkbp:GO
|
GO:0005525
GO:0003924
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
RalB GTPase
|
|
gptkbp:inactiveForm
|
GDP-bound
|
|
gptkbp:interactsWith
|
gptkb:RalBP1
gptkb:Sec5
Exocyst complex
|
|
gptkbp:involvedIn
|
cell proliferation
vesicle trafficking
autophagy
innate immune response
|
|
gptkbp:length
|
206 amino acids
|
|
gptkbp:locatedOnChromosome
|
2q37.1
|
|
gptkbp:memberOf
|
gptkb:Ras_superfamily
Ral GTPase family
|
|
gptkbp:molecularWeight
|
23 kDa
|
|
gptkbp:OMIM
|
179550
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:PDB
|
2KE5
|
|
gptkbp:postTranslationalModification
|
prenylation
phosphorylation
|
|
gptkbp:RefSeq
|
NP_005457
|
|
gptkbp:regulates
|
apoptosis
cell migration
activated by GEFs
endocytosis
exocytosis
inactivated by GAPs
tumorigenesis
regulated by GDP/GTP exchange
|
|
gptkbp:relatedTo
|
gptkb:RalA_GTPase
|
|
gptkbp:reviewedBy
|
gptkb:UniProtKB/Swiss-Prot
|
|
gptkbp:structure
|
contains GTPase domain
|
|
gptkbp:subcellularLocation
|
gptkb:cytoplasm
gptkb:plasma_membrane
endosomes
|
|
gptkbp:UniProtID
|
Q15382
|
|
gptkbp:bfsParent
|
gptkb:Ral-GDS_pathway
|
|
gptkbp:bfsLayer
|
7
|