|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:central_core_disease
malignant hyperthermia
|
|
gptkbp:diseaseMutation
|
gptkb:central_core_disease
gptkb:multiminicore_disease
malignant hyperthermia susceptibility
|
|
gptkbp:EC_number
|
2.7.11.1
|
|
gptkbp:encodedBy
|
gptkb:RYR1_gene
|
|
gptkbp:Entrez_Gene_ID
|
6266
|
|
gptkbp:foundIn
|
gptkb:skeletal_muscle
|
|
gptkbp:function
|
calcium release channel
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
RYR1 protein
|
|
gptkbp:interactsWith
|
gptkb:calmodulin
gptkb:FKBP12
gptkb:dihydropyridine_receptor
|
|
gptkbp:length
|
5038 amino acids
|
|
gptkbp:locatedOnChromosome
|
19q13.2
|
|
gptkbp:location
|
sarcoplasmic reticulum
|
|
gptkbp:molecularWeight
|
565 kDa
|
|
gptkbp:OMIM
|
180901
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:PDB
|
gptkb:5TAL
gptkb:5T15
5TB0
|
|
gptkbp:postTranslationalModification
|
phosphorylation
oxidation
S-nitrosylation
|
|
gptkbp:structure
|
homotetramer
|
|
gptkbp:subunit
|
tetramer
|
|
gptkbp:UniProtID
|
P21817
|
|
gptkbp:bfsParent
|
gptkb:Ryr1
|
|
gptkbp:bfsLayer
|
7
|