RXFP1

GPTKB entity

Statements (36)
Predicate Object
gptkbp:instanceOf gptkb:gene
gptkbp:alternativeName Leucine-rich repeat-containing G-protein coupled receptor 7
LGR7
gptkbp:associatedWith heart failure
fibrosis
preterm birth
vasodilation
reproductive system regulation
fibrosis modulation
gptkbp:discoveredBy Hsu et al.
gptkbp:discoveredIn 2002
gptkbp:encodes Relaxin family peptide receptor 1 protein
gptkbp:Entrez_Gene_ID 59350
ENSG00000174444
gptkbp:expressedIn gptkb:kidney
brain
heart
reproductive tissues
gptkbp:fullName relaxin/insulin-like family peptide receptor 1
gptkbp:function gptkb:G_protein-coupled_receptor
gptkbp:geneType protein-coding
gptkbp:hasLeucineRichRepeats yes
gptkbp:HGNC_ID HGNC:16854
https://www.w3.org/2000/01/rdf-schema#label RXFP1
gptkbp:ligand gptkb:relaxin
gptkbp:locatedOnChromosome 4q31.3
gptkbp:OMIM 606654
gptkbp:organism gptkb:Homo_sapiens
gptkbp:orthologInMouse Rxfp1
gptkbp:pathway GPCR signaling pathway
relaxin signaling pathway
gptkbp:proteinFamily gptkb:G_protein-coupled_receptor
gptkbp:transmembraneDomains yes
gptkbp:UniProtID Q9HBX9
gptkbp:bfsParent gptkb:relaxin
gptkbp:bfsLayer 6