relaxin

GPTKB entity

Statements (35)
Predicate Object
gptkbp:instanceOf hormone
gptkbp:CASNumber gptkb:60644-46-8
gptkbp:discoveredBy gptkb:Frederick_Hisaw
gptkbp:discoveredIn 1926
gptkbp:foundIn humans
other mammals
gptkbp:function increases cardiac output
increases renal blood flow
inhibits uterine contractions
regulates collagen metabolism
relaxes ligaments in the pelvis
softens and widens the cervix during childbirth
gptkbp:gene gptkb:RLN1
gptkb:RLN2
https://www.w3.org/2000/01/rdf-schema#label relaxin
gptkbp:medicalUse potential treatment for fibrosis
potential treatment for heart failure
potential treatment for scleroderma
gptkbp:MeSH_ID gptkb:D011929
gptkbp:producedBy gptkb:placenta
brain
heart
prostate gland
uterus
ovaries
corpus luteum
gptkbp:PubChem_CID gptkb:CHEBI:8016
gptkbp:recipient gptkb:RXFP1
gptkb:RXFP2
gptkbp:relatedTo gptkb:insulin
gptkbp:structure peptide
two peptide chains (A and B) linked by disulfide bonds
gptkbp:UNII Q157X3JZ55
gptkbp:bfsParent gptkb:testis
gptkbp:bfsLayer 5