|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeName
|
ECP-51
Pontin-2
Reptin
TIH2
TIP48
TIP49B
|
|
gptkbp:associatedWith
|
gptkb:cancer
apoptosis
cell proliferation
cell cycle regulation
|
|
gptkbp:component
|
INO80 complex
R2TP complex
TIP60 complex
|
|
gptkbp:discoveredBy
|
1999
|
|
gptkbp:encodes
|
gptkb:RuvB-like_2_protein
|
|
gptkbp:Entrez_Gene_ID
|
ENSG00000100320
10856
|
|
gptkbp:expressedIn
|
various human tissues
|
|
gptkbp:function
|
ATPase activity
DNA helicase activity
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:GO
|
gptkb:GO:0006355_(regulation_of_transcription,_DNA-templated)
GO:0005524 (ATP binding)
GO:0005634 (nucleus)
GO:0003678 (DNA helicase activity)
|
|
gptkbp:HGNC_ID
|
HGNC:10470
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
RUVBL2
|
|
gptkbp:interactsWith
|
PIH1D1
RPAP3
RUVBL1
|
|
gptkbp:involvedIn
|
DNA repair
transcription regulation
chromatin remodeling
|
|
gptkbp:length
|
463 amino acids
|
|
gptkbp:locatedIn
|
gptkb:Homo_sapiens
|
|
gptkbp:locatedOnChromosome
|
19
|
|
gptkbp:molecularWeight
|
51 kDa
|
|
gptkbp:OMIM
|
604068
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Drosophila_melanogaster
|
|
gptkbp:PDB
|
2C9O
2XSZ
|
|
gptkbp:proteinFamily
|
PF00004 (AAA domain)
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:UniProtID
|
Q9Y265
|
|
gptkbp:bfsParent
|
gptkb:RUVBG
|
|
gptkbp:bfsLayer
|
7
|