|
gptkbp:instanceOf
|
gptkb:drug
|
|
gptkbp:administeredBy
|
gptkb:misoprostol
|
|
gptkbp:alsoKnownAs
|
gptkb:mifepristone
|
|
gptkbp:approvalYear
|
1988
|
|
gptkbp:approvedBy
|
gptkb:China
gptkb:France
gptkb:India
gptkb:United_Kingdom
gptkb:United_States
|
|
gptkbp:ATCCode
|
G03XB01
|
|
gptkbp:CASNumber
|
gptkb:84371-65-3
|
|
gptkbp:category
|
gptkb:Corticosteroid
oral contraceptive
abortifacient
hormone antagonist
|
|
gptkbp:chemicalFormula
|
gptkb:C29H35NO2
|
|
gptkbp:contraindication
|
ectopic pregnancy
long-term corticosteroid therapy
chronic adrenal failure
|
|
gptkbp:developedBy
|
Émile-Étienne Baulieu
|
|
gptkbp:discoveredBy
|
Roussel Uclaf
|
|
gptkbp:discoveredIn
|
1980
|
|
gptkbp:eliminationHalfLife
|
18 hours
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
RU-486
|
|
gptkbp:legalStatus
|
varies by country
prescription only
off-patent
|
|
gptkbp:marketedAs
|
gptkb:France
Danco Laboratories
Exelgyn
Linepharma
|
|
gptkbp:mechanismOfAction
|
progesterone receptor antagonist
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
429.6 g/mol
|
|
gptkbp:pregnancyCategory
|
X
|
|
gptkbp:pregnancyTermination
|
up to 10 weeks gestation
|
|
gptkbp:PubChem_CID
|
55245
DB00834
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
nausea
abdominal pain
fatigue
headache
vaginal bleeding
|
|
gptkbp:UNII
|
320T6RNW1F
|
|
gptkbp:usedFor
|
oral contraceptive
medical abortion
management of miscarriage
|
|
gptkbp:WHOModelListOfEssentialMedicines
|
included
|
|
gptkbp:bfsParent
|
gptkb:Glucocorticoid_receptor
gptkb:Mifepristone
|
|
gptkbp:bfsLayer
|
7
|