|
gptkbp:instanceOf
|
gptkb:drug
prostaglandin analogue
|
|
gptkbp:approvalYear
|
1988
|
|
gptkbp:approvedBy
|
gptkb:FDA
|
|
gptkbp:ATCCode
|
A02BB01
|
|
gptkbp:availableOn
|
gptkb:tablet
|
|
gptkbp:brand
|
Cytotec
MisoOne
Misotrol
|
|
gptkbp:CASNumber
|
59122-46-2
|
|
gptkbp:category
|
abortifacient
gastroprotective agent
uterotonic agent
|
|
gptkbp:chemicalFormula
|
C22H38O5
|
|
gptkbp:combines
|
gptkb:mifepristone
|
|
gptkbp:contraindication
|
allergy to prostaglandins
pregnancy (unless for abortion or labor induction)
|
|
gptkbp:developedBy
|
gptkb:G.D._Searle_&_Company
|
|
gptkbp:discoveredIn
|
1973
|
|
gptkbp:eliminationHalfLife
|
20–40 minutes
|
|
gptkbp:excretion
|
urine
|
|
gptkbp:foundIn
|
World Health Organization Essential Medicines List
|
|
gptkbp:genericName
|
yes
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
misoprostol
|
|
gptkbp:KEGGID
|
D00413
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
prostaglandin E1 analogue
|
|
gptkbp:MedlinePlusID
|
a689009
|
|
gptkbp:MeSH_ID
|
D016297
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:patentExpired
|
yes
|
|
gptkbp:pregnancyCategory
|
X (contraindicated in pregnancy except for specific indications)
|
|
gptkbp:PubChem_CID
|
CHEMBL1201
5282381
DB00929
|
|
gptkbp:routeOfAdministration
|
oral
vaginal
sublingual
buccal
|
|
gptkbp:sideEffect
|
fever
nausea
diarrhea
abdominal pain
chills
|
|
gptkbp:UNII
|
0E43V0BB57
|
|
gptkbp:usedFor
|
medical abortion
induction of labor
treatment of postpartum hemorrhage
prevention of gastric ulcers
|
|
gptkbp:WHOModelListOfEssentialMedicines
|
included
|
|
gptkbp:bfsParent
|
gptkb:Medical_Termination_of_Pregnancy
gptkb:Mifepristone
|
|
gptkbp:bfsLayer
|
7
|