RNase III

GPTKB entity

Statements (29)
Predicate Object
gptkbp:instanceOf gptkb:enzyme
gptkbp:biologicalProcess endoribonuclease activity
gptkbp:catalyzes cleavage of double-stranded RNA
gptkbp:cofactor Mg2+
gptkbp:discoveredBy A. J. S. Klar
gptkbp:discoveredIn 1968
gptkbp:domain RNase III domain
gptkbp:enzymeCommissionNumber EC 3.1.26.3
gptkbp:family RNase III family
gptkbp:foundIn gptkb:Bacteria
archaea
eukaryotes
gptkbp:gene rnc
gptkbp:GO_term GO:0004525
https://www.w3.org/2000/01/rdf-schema#label RNase III
gptkbp:involvedIn gene silencing
mRNA degradation
RNA processing
rRNA maturation
gptkbp:orthologIn gptkb:Dicer
gptkb:Drosha
gptkbp:product short double-stranded RNA fragments
gptkbp:proteinFamily PF00636
gptkbp:regulates gene expression
gptkbp:structure homodimer
gptkbp:substrate double-stranded RNA
gptkbp:UniProtID P0A7Y0
gptkbp:bfsParent gptkb:Ribonuclease
gptkbp:bfsLayer 7