RING-between-RING E3 ligases
GPTKB entity
Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
RBR E3 ligases
|
| gptkbp:associatedWith |
gptkb:Parkinson's_disease
|
| gptkbp:discoveredBy |
Deshaies lab
|
| gptkbp:domain |
gptkb:IBR_domain
gptkb:RING1_domain gptkb:RING2_domain |
| gptkbp:example |
gptkb:Parkin
gptkb:HHARI gptkb:HOIP gptkb:RNF144A RNF216 |
| gptkbp:firstDescribed |
2003
|
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:function |
ubiquitin ligase activity
|
| gptkbp:GO_term |
gptkb:GO:0061630
|
| https://www.w3.org/2000/01/rdf-schema#label |
RING-between-RING E3 ligases
|
| gptkbp:involvedIn |
ubiquitination
|
| gptkbp:mechanismOfAction |
catalyze ubiquitin transfer via thioester intermediate
|
| gptkbp:relatedTo |
HECT-type E3 ligases
RING-type E3 ligases |
| gptkbp:bfsParent |
gptkb:RBR_E3_ubiquitin_ligase_family
|
| gptkbp:bfsLayer |
8
|