RAB5A, member RAS oncogene family

URI: https://gptkb.org/entity/RAB5A,_member_RAS_oncogene_family
GPTKB entity
Statements (48)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alias gptkb:RAB5
gptkb:RAB5A
gptkbp:associatedWith gptkb:Alzheimer's_disease
gptkb:cancer
gptkbp:biologicalProcess GTPase activity
endocytosis
vesicle-mediated transport
gptkbp:cellularComponent gptkb:cytoplasm
early endosome membrane
gptkbp:encodes gptkb:Ras-related_protein_Rab-5A
gptkbp:Entrez_Gene_ID 5868
ENSG00000144566
gptkbp:family gptkb:Ras_superfamily
gptkbp:function early endosome fusion
regulation of endocytic vesicle trafficking
gptkbp:gene gptkb:RAB5A
gptkbp:geneType protein-coding
https://www.w3.org/2000/01/rdf-schema#label RAB5A, member RAS oncogene family
gptkbp:interactsWith gptkb:RIN1
gptkb:RIN2
gptkb:RIN3
gptkb:EEA1
gptkb:GDI1
gptkb:GDI2
RABEP1
RABGEF1
gptkbp:length 215
gptkbp:locatedOnChromosome 3p24.3
gptkbp:molecularWeight 23.7 kDa
gptkbp:organism gptkb:Homo_sapiens
gptkbp:orthologInMouse gptkb:Rab5a
gptkbp:postTranslationalModification prenylation
phosphorylation
gptkbp:regulates cell proliferation
cell migration
autophagy
receptor-mediated endocytosis
EGFR trafficking
phagosome maturation
endosome dynamics
macropinocytosis
gptkbp:subcellularLocation gptkb:plasma_membrane
gptkb:early_endosome
gptkbp:subfamily gptkb:Rab_family
gptkbp:UniProtID P20339
gptkbp:bfsParent gptkb:RAB5A_gene
gptkbp:bfsLayer 7