Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:PDZ-GEF1
RAP guanine nucleotide exchange factor 2 |
| gptkbp:associatedWith |
signal transduction
|
| gptkbp:domain |
PDZ domain
RA domain Ras-GEF domain |
| gptkbp:encodedBy |
RAPGEF2 gene
|
| gptkbp:expressedIn |
gptkb:kidney
gptkb:testis brain heart |
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
guanine nucleotide exchange factor
activates Rap1 activates Rap2 |
| gptkbp:gene |
gptkb:RAPGEF2
|
| https://www.w3.org/2000/01/rdf-schema#label |
RA-GEF-2
|
| gptkbp:interactsWith |
gptkb:Epac
gptkb:cAMP gptkb:Rap1 gptkb:Rap2 |
| gptkbp:locatedOnChromosome |
chromosome 4q32-q33
|
| gptkbp:location |
gptkb:cytoplasm
gptkb:plasma_membrane |
| gptkbp:molecularWeight |
~180 kDa
|
| gptkbp:OMIM |
605370
|
| gptkbp:UniProtID |
O95267
|
| gptkbp:bfsParent |
gptkb:RAPGEF2
gptkb:RAPGEF20 gptkb:RAPGEF27 gptkb:RAPGEF7 |
| gptkbp:bfsLayer |
7
|