Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:Rap_guanine_nucleotide_exchange_factor_2
RA-GEF-1 |
| gptkbp:domain |
PDZ domain
RasGEF domain |
| gptkbp:encodedBy |
RapGEF2 gene
|
| gptkbp:Entrez_Gene_ID |
23365
|
| gptkbp:expressedIn |
gptkb:kidney
brain heart liver |
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
guanine nucleotide exchange factor
|
| https://www.w3.org/2000/01/rdf-schema#label |
PDZ-GEF1
|
| gptkbp:interactsWith |
gptkb:Rap1
gptkb:Rap2 |
| gptkbp:involvedIn |
cell signaling
cell adhesion |
| gptkbp:locale |
gptkb:cytoplasm
gptkb:plasma_membrane |
| gptkbp:locatedOnChromosome |
4q32-q33
|
| gptkbp:molecularWeight |
~130 kDa
|
| gptkbp:OMIM |
605453
|
| gptkbp:phosphorylates |
Serine 548
Threonine 573 |
| gptkbp:regulates |
gptkb:cAMP_signaling_pathway
integrin-mediated cell adhesion |
| gptkbp:UniProtID |
Q8WZA2
|
| gptkbp:bfsParent |
gptkb:RAPGEF12
gptkb:RAPGEF2 gptkb:RAPGEF7 |
| gptkbp:bfsLayer |
7
|