Parkinson-plus syndrome

GPTKB entity

Statements (31)
Predicate Object
gptkbp:instanceOf neurological disorder
gptkbp:affects central nervous system
gptkbp:alsoKnownAs gptkb:atypical_parkinsonism
gptkbp:causedBy degeneration of specific brain regions
gptkbp:characterizedBy parkinsonism with additional features
gptkbp:diagnosedBy neuroimaging
clinical evaluation
gptkbp:differentialDiagnosis gptkb:Parkinson's_disease
gptkbp:firstDescribed mid-20th century
https://www.w3.org/2000/01/rdf-schema#label Parkinson-plus syndrome
gptkbp:ICD-10_code G23.1
gptkbp:includes gptkb:dementia_with_Lewy_bodies
gptkb:corticobasal_degeneration
gptkb:multiple_system_atrophy
gptkb:progressive_supranuclear_palsy
gptkbp:notableFeature poor response to dopaminergic therapy
gptkbp:prognosis generally worse than Parkinson's disease
gptkbp:riskFactor age
gptkbp:subspecies gptkb:dementia_with_Lewy_bodies
gptkb:corticobasal_degeneration
gptkb:multiple_system_atrophy
gptkb:progressive_supranuclear_palsy
gptkbp:symptom bradykinesia
postural instability
rigidity
cognitive impairment
autonomic dysfunction
poor response to levodopa
gptkbp:treatment symptomatic management
gptkbp:bfsParent gptkb:atypical_parkinsonism
gptkbp:bfsLayer 8