Statements (44)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
autoimmune disease
paraneoplastic syndrome mucocutaneous disease |
| gptkbp:affects |
gptkb:skin
lungs mucous membranes |
| gptkbp:alternativeName |
gptkb:PNP
paraneoplastic autoimmune multiorgan syndrome |
| gptkbp:associatedWith |
gptkb:Castleman_disease
leukemia thymoma chronic lymphocytic leukemia lymphoproliferative disorders underlying neoplasm |
| gptkbp:cause |
bronchiolitis obliterans
|
| gptkbp:diagnosedBy |
gptkb:ELISA
histopathology immunofluorescence |
| gptkbp:field |
immunology
oncology dermatology |
| gptkbp:firstDescribed |
1990
|
| gptkbp:hasAutoantibody |
gptkb:desmoglein_1
gptkb:desmoglein_3 desmoplakin BP230 alpha-2-macroglobulin-like-1 protein envoplakin periplakin |
| https://www.w3.org/2000/01/rdf-schema#label |
Paraneoplastic pemphigus
|
| gptkbp:ICD-10_code |
L10.8
|
| gptkbp:mortalityRate |
high
|
| gptkbp:prognosis |
poor
|
| gptkbp:symptom |
blistering skin lesions
oral ulcerations painful mucosal erosions polymorphous skin eruptions |
| gptkbp:treatment |
gptkb:rituximab
gptkb:IVIG plasmapheresis immunosuppressive agents systemic corticosteroids |
| gptkbp:bfsParent |
gptkb:Pemphigus
|
| gptkbp:bfsLayer |
7
|