|
gptkbp:instanceOf
|
gptkb:drug
proton pump inhibitor
|
|
gptkbp:approvedBy
|
1994
|
|
gptkbp:ATCCode
|
gptkb:A02BC02
|
|
gptkbp:bioavailability
|
77%
|
|
gptkbp:brand
|
gptkb:Pantoloc
gptkb:Somac
gptkb:Protonix
Controloc
Pantozol
|
|
gptkbp:CASNumber
|
102625-70-7
|
|
gptkbp:category
|
benzimidazole derivative
|
|
gptkbp:contraindication
|
hypersensitivity to pantoprazole
|
|
gptkbp:developedBy
|
gptkb:Byk_Gulden
|
|
gptkbp:drugClass
|
proton pump inhibitor
|
|
gptkbp:eliminationHalfLife
|
1 hour
|
|
gptkbp:excretion
|
urine
feces
|
|
gptkbp:FDAApproved
|
2000
|
|
gptkbp:hasMolecularFormula
|
C16H15F2N3O4S
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Pantoprazole
|
|
gptkbp:interactsWith
|
gptkb:warfarin
gptkb:clopidogrel
gptkb:methotrexate
gptkb:atazanavir
|
|
gptkbp:KEGGID
|
D05322
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
inhibits H+/K+ ATPase in gastric parietal cells
|
|
gptkbp:metabolism
|
liver
desmethylpantoprazole
|
|
gptkbp:molecularWeight
|
383.37 g/mol
|
|
gptkbp:pregnancyCategory
|
B (US)
B3 (Australia)
|
|
gptkbp:prescriptionStatus
|
prescription only
|
|
gptkbp:proteinBinding
|
98%
|
|
gptkbp:PubChem_CID
|
4517
4679
CHEMBL1502
DB00213
|
|
gptkbp:routeOfAdministration
|
oral
intravenous
|
|
gptkbp:sideEffect
|
nausea
diarrhea
abdominal pain
dizziness
headache
|
|
gptkbp:UNII
|
3E0G7GA6CB
|
|
gptkbp:usedFor
|
gptkb:Zollinger-Ellison_syndrome
gptkb:gastroesophageal_reflux_disease
gptkb:peptic_ulcer_disease
|
|
gptkbp:WHOModelListOfEssentialMedicines
|
included
|
|
gptkbp:bfsParent
|
gptkb:Takeda_Pharmaceutical_Company
gptkb:Nycomed
gptkb:Zentiva
|
|
gptkbp:bfsLayer
|
7
|