Statements (25)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alternativeName |
gptkb:LYP
gptkb:PTP-N22 gptkb:protein_tyrosine_phosphatase,_non-receptor_type_22 |
| gptkbp:associatedWith |
gptkb:systemic_lupus_erythematosus
Graves' disease type 1 diabetes autoimmune diseases rheumatoid arthritis |
| gptkbp:encodes |
gptkb:protein_tyrosine_phosphatase_non-receptor_type_22
|
| gptkbp:Entrez_Gene_ID |
26191
|
| gptkbp:expressedIn |
immune cells
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
negative regulation of immune response
regulation of T-cell receptor signaling |
| gptkbp:hasVariant |
gptkb:R620W
|
| gptkbp:HGNC_ID |
9644
|
| https://www.w3.org/2000/01/rdf-schema#label |
PTPN22
|
| gptkbp:locatedOnChromosome |
chromosome 1
|
| gptkbp:orthologInMouse |
Ptpn22
|
| gptkbp:product |
gptkb:Lyp
|
| gptkbp:R620WVariantAssociatedWith |
increased risk of autoimmunity
|
| gptkbp:UniProtID |
gptkb:Q9Y2R2
|
| gptkbp:bfsParent |
gptkb:protein_tyrosine_phosphatases
|
| gptkbp:bfsLayer |
6
|