PSP-parkinsonism

GPTKB entity

Statements (29)
Predicate Object
gptkbp:instanceOf gptkb:atypical_parkinsonism
neurological disorder
gptkbp:associatedWith older adults
gptkbp:category movement disorder
gptkbp:cause tau protein accumulation
gptkbp:diagnosedBy clinical evaluation
MRI (midbrain atrophy)
gptkbp:differentialDiagnosis gptkb:Parkinson's_disease
gptkb:corticobasal_degeneration
gptkb:multiple_system_atrophy
gptkbp:firstDescribed 1990s
gptkbp:geneticStudies gptkb:MAPT_gene
https://www.w3.org/2000/01/rdf-schema#label PSP-parkinsonism
gptkbp:prevalence less common than classic PSP-Richardson's syndrome
gptkbp:progression slower than classic PSP
gptkbp:subspecies gptkb:progressive_supranuclear_palsy
gptkbp:symptom bradykinesia
falls
postural instability
rigidity
tremor
dysphagia
dysarthria
supranuclear gaze palsy
gptkbp:treatment physical therapy
speech therapy
levodopa (limited response)
gptkbp:bfsParent gptkb:Progressive_Supranuclear_Palsy
gptkbp:bfsLayer 7