PSP-Richardson's syndrome

GPTKB entity

Statements (39)
Predicate Object
gptkbp:instanceOf gptkb:atypical_parkinsonism
neurodegenerative disease
gptkbp:affects gptkb:basal_ganglia
brainstem
midbrain
gptkbp:alsoKnownAs Progressive Supranuclear Palsy - Richardson's syndrome
gptkbp:causedBy tau protein accumulation
gptkbp:diagnosedBy MRI
clinical criteria
gptkbp:differentialDiagnosis gptkb:Parkinson's_disease
gptkb:corticobasal_degeneration
gptkb:multiple_system_atrophy
gptkbp:firstDescribed 1963
J. Clifford Richardson
https://www.w3.org/2000/01/rdf-schema#label PSP-Richardson's syndrome
gptkbp:ICD-10_code G23.1
gptkbp:mortalityRate high
gptkbp:OMIM 601104
gptkbp:onset late adulthood
gptkbp:partOf Progressive Supranuclear Palsy (PSP)
gptkbp:prevalence rare
gptkbp:prognosis progressive
poor
gptkbp:relatedTo gptkb:PSP-parkinsonism
PSP-pure akinesia with gait freezing
gptkbp:riskFactor age
genetic predisposition
gptkbp:symptom bradykinesia
postural instability
cognitive impairment
dysphagia
dysarthria
vertical gaze palsy
axial rigidity
gptkbp:treatment supportive care
physical therapy
speech therapy
gptkbp:bfsParent gptkb:Progressive_Supranuclear_Palsy
gptkbp:bfsLayer 7