|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
CD162
|
|
gptkbp:discoveredBy
|
Rosen SD
|
|
gptkbp:discoveredIn
|
1994
|
|
gptkbp:Entrez_Gene_ID
|
ENSG00000110880
|
|
gptkbp:expressedIn
|
gptkb:leukocytes
gptkb:B_cells
gptkb:T_cells
monocytes
neutrophils
|
|
gptkbp:foundIn
|
humans
mice
|
|
gptkbp:fullName
|
P-selectin glycoprotein ligand-1
|
|
gptkbp:function
|
mediates leukocyte rolling
binds selectins
|
|
gptkbp:gene
|
SELPLG
|
|
gptkbp:HGNC_ID
|
10721
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PSGL-1
|
|
gptkbp:interactsWith
|
gptkb:P-selectin
gptkb:E-selectin
L-selectin
|
|
gptkbp:ligand
|
gptkb:P-selectin
gptkb:E-selectin
L-selectin
|
|
gptkbp:locatedOnChromosome
|
gptkb:12q24.11
|
|
gptkbp:location
|
cell surface
|
|
gptkbp:molecularWeight
|
120 kDa
|
|
gptkbp:OMIM
|
600738
|
|
gptkbp:postTranslationalModification
|
glycosylation
tyrosine sulfation
|
|
gptkbp:role
|
HIV infection
atherosclerosis
immunotherapy
autoimmune diseases
inflammation
immune response
cancer metastasis
host defense
adhesion
T cell exhaustion
leukocyte trafficking
extravasation
viral restriction
|
|
gptkbp:structure
|
mucin-like glycoprotein
|
|
gptkbp:target
|
therapeutic antibodies
small molecule inhibitors
|
|
gptkbp:UniProtID
|
Q14242
|
|
gptkbp:bfsParent
|
gptkb:P-selectin
|
|
gptkbp:bfsLayer
|
7
|