|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
1-Cys peroxiredoxin
Antioxidant protein 2
Liver-specific 28 kDa protein
NSGPx
Peroxiredoxin VI
p29
thiol-specific antioxidant protein
|
|
gptkbp:domain
|
thioredoxin domain
|
|
gptkbp:encodedBy
|
PRDX6 gene
|
|
gptkbp:Entrez_Gene_ID
|
9588
|
|
gptkbp:enzymeCommissionNumber
|
EC 1.11.1.21
EC 3.1.1.4
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:kidney
gptkb:testis
brain
heart
liver
pancreas
|
|
gptkbp:foundIn
|
cytosol
extracellular exosome
|
|
gptkbp:fullName
|
Peroxiredoxin-6
|
|
gptkbp:function
|
antioxidant activity
peroxidase activity
phospholipase A2 activity
|
|
gptkbp:gene
|
gptkb:PRDX6
|
|
gptkbp:HGNC_ID
|
HGNC:9350
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PRDX6
|
|
gptkbp:involvedIn
|
cellular response to oxidative stress
lung surfactant metabolism
phospholipid metabolism
|
|
gptkbp:locatedOnChromosome
|
1q25
|
|
gptkbp:location
|
gptkb:lysosome
gptkb:cytoplasm
|
|
gptkbp:molecularWeight
|
25-28 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:cancer
lung injury
|
|
gptkbp:OMIM
|
602425
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Danio_rerio
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:PDB
|
1PRX
5B6M
5B6N
|
|
gptkbp:RefSeq
|
NM_004905
|
|
gptkbp:regulates
|
reactive oxygen species
phospholipid homeostasis
|
|
gptkbp:UniProtID
|
gptkb:P30041
|
|
gptkbp:bfsParent
|
gptkb:1R8Q
|
|
gptkbp:bfsLayer
|
7
|