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gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:GADD34
|
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gptkbp:associatedWith
|
cell cycle regulation
apoptosis regulation
|
|
gptkbp:discoveredBy
|
Ron Prywes et al.
|
|
gptkbp:encodes
|
gptkb:protein_phosphatase_1_regulatory_subunit_15A
|
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gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000101323
23645
|
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gptkbp:expressedIn
|
various human tissues
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|
gptkbp:firstDescribed
|
1996
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gptkbp:function
|
cellular stress response
regulation of protein phosphatase 1 activity
|
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gptkbp:geneType
|
protein coding
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PPP1R15A
|
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gptkbp:inducedBy
|
DNA damage
endoplasmic reticulum stress
|
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gptkbp:interactsWith
|
gptkb:protein_phosphatase_1
gptkb:eIF2α
|
|
gptkbp:involvedIn
|
endoplasmic reticulum stress response
dephosphorylation of eIF2α
|
|
gptkbp:length
|
674 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_19
|
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gptkbp:molecularWeight
|
74 kDa
|
|
gptkbp:OMIM
|
603557
|
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gptkbp:organism
|
gptkb:Homo_sapiens
|
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gptkbp:orthologInMouse
|
gptkb:Ppp1r15a
|
|
gptkbp:regulates
|
protein synthesis
|
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gptkbp:subcellularLocation
|
gptkb:endoplasmic_reticulum
gptkb:cytoplasm
|
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gptkbp:UniProtID
|
gptkb:Q9NZJ5
|
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gptkbp:bfsParent
|
gptkb:19p13.3
|
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gptkbp:bfsLayer
|
6
|