GADD34

GPTKB entity

Statements (25)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName gptkb:protein_phosphatase_1_regulatory_subunit_15A
MyD116
gptkbp:associatedWith apoptosis
cellular stress
gptkbp:discoveredIn 1997
gptkbp:encodedBy gptkb:PPP1R15A
gptkbp:fullName Growth arrest and DNA-damage-inducible protein 34
gptkbp:function involved in stress response
promotes dephosphorylation of eIF2α
regulates protein phosphatase 1 activity
gptkbp:gene gptkb:PPP1R15A
https://www.w3.org/2000/01/rdf-schema#label GADD34
gptkbp:interactsWith gptkb:protein_phosphatase_1
gptkb:eIF2α
gptkbp:locatedOnChromosome 19q13.33
gptkbp:location gptkb:endoplasmic_reticulum
gptkbp:organism gptkb:Homo_sapiens
gptkbp:regulates protein synthesis
unfolded protein response
gptkbp:upregulatedBy DNA damage
endoplasmic reticulum stress
growth arrest
gptkbp:bfsParent gptkb:PPP1R15A
gptkbp:bfsLayer 7