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gptkbp:instanceOf
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gptkb:gene
|
|
gptkbp:alternativeName
|
PLC-beta-2
phosphoinositide phospholipase C-beta-2
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|
gptkbp:associatedWith
|
immune response
inflammatory signaling
|
|
gptkbp:biologicalProcess
|
phospholipase activity
phosphoinositide-mediated signaling
cellular response to stimulus
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gptkbp:cellularComponent
|
gptkb:cytoplasm
gptkb:plasma_membrane
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gptkbp:encodes
|
phospholipase C beta 2
|
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gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000137845
5331
|
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gptkbp:expressedIn
|
immune system
hematopoietic cells
|
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gptkbp:function
|
generates second messengers IP3 and DAG
hydrolyzes phosphatidylinositol 4,5-bisphosphate
|
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gptkbp:HGNC_ID
|
9067
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PLCB2
|
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gptkbp:involvedIn
|
signal transduction
phosphoinositide pathway
|
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gptkbp:locatedOnChromosome
|
15q15
|
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gptkbp:OMIM
|
600820
|
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gptkbp:organism
|
gptkb:Homo_sapiens
|
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gptkbp:orthologInMouse
|
Plcb2
|
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gptkbp:proteinFamily
|
gptkb:phospholipase_C_family
|
|
gptkbp:regulates
|
activated by G-protein alpha subunits
activated by G-protein beta-gamma subunits
|
|
gptkbp:UniProtID
|
Q00722
|
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gptkbp:bfsParent
|
gptkb:phospholipase_C
|
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gptkbp:bfsLayer
|
6
|