PI3-kinase p110-beta

URI: https://gptkb.org/entity/PI3-kinase_p110-beta
GPTKB entity
Statements (26)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName gptkb:PIK3CB
phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
gptkbp:catalyzes phosphorylation of phosphatidylinositol-4,5-bisphosphate to phosphatidylinositol-3,4,5-trisphosphate
gptkbp:encodedBy gptkb:PIK3CB_gene
gptkbp:enzymeCommissionNumber gptkb:EC_2.7.1.153
gptkbp:expressedIn gptkb:human
gptkb:mouse
https://www.w3.org/2000/01/rdf-schema#label PI3-kinase p110-beta
gptkbp:interactsWith regulatory subunit p85
gptkbp:involvedIn gptkb:PI3K/AKT_signaling_pathway
cell survival
cancer progression
cell growth
cell migration
insulin signaling
gptkbp:locatedIn gptkb:cytoplasm
gptkb:plasma_membrane
gptkbp:locatedOnChromosome gptkb:chromosome_3q22.3
gptkbp:molecularWeight ~110 kDa
gptkbp:subunit gptkb:phosphoinositide_3-kinase_(PI3K)_class_IA
gptkbp:target PI3K inhibitors
gptkbp:UniProtID gptkb:P42338
gptkbp:bfsParent gptkb:PIK3CB_(p110β)
gptkb:phosphatidylinositol-4,5-bisphosphate_3-kinase_catalytic_subunit_beta_isoform
gptkbp:bfsLayer 6