Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
Polyadenylate-binding protein
|
| gptkbp:associatedWith |
Oculopharyngeal muscular dystrophy (PABPN1 mutation)
|
| gptkbp:domain |
RNA recognition motif (RRM)
|
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:fullName |
Poly(A)-binding proteins
|
| gptkbp:function |
bind polyadenylate sequences in mRNA
|
| gptkbp:GO_term |
GO:0006417 (regulation of translation)
GO:0003723 (RNA binding) GO:0006402 (mRNA catabolic process) |
| https://www.w3.org/2000/01/rdf-schema#label |
PABP proteins
|
| gptkbp:interactsWith |
gptkb:eIF4G
mRNA poly(A) tail |
| gptkbp:locale |
gptkb:nucleus
gptkb:cytoplasm |
| gptkbp:member |
gptkb:PABPC1
gptkb:PABPN1 PABPC4 |
| gptkbp:orthologIn |
Arabidopsis PABP
Drosophila PABP yeast Pab1 |
| gptkbp:regulates |
post-translational modifications
|
| gptkbp:role |
mRNA decay
regulation of translation mRNA export regulation of mRNA stability |
| gptkbp:structure |
C-terminal PABC domain
multiple RRM domains |
| gptkbp:bfsParent |
gptkb:RRM_domain
|
| gptkbp:bfsLayer |
7
|