|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
Nuclear poly(A)-binding protein
PABP2
|
|
gptkbp:associatedWith
|
oculopharyngeal muscular dystrophy
|
|
gptkbp:encodedBy
|
PABPN1 gene
|
|
gptkbp:Entrez_Gene_ID
|
ENSG00000125818
8106
|
|
gptkbp:fullName
|
Polyadenylate-binding nuclear protein 1
|
|
gptkbp:function
|
binds to poly(A) tails of mRNA
regulates polyadenylation
|
|
gptkbp:gene
|
gptkb:PABPN1
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PABPN1
|
|
gptkbp:interactsWith
|
CPSF
poly(A) polymerase
|
|
gptkbp:length
|
306 amino acids
|
|
gptkbp:locatedOnChromosome
|
20q13.33
|
|
gptkbp:location
|
gptkb:nucleus
|
|
gptkbp:molecularWeight
|
32 kDa
|
|
gptkbp:mutationAssociatedWith
|
expansion of GCG repeat causes OPMD
|
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gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Pabpn1
|
|
gptkbp:orthologInYeast
|
Nab2
|
|
gptkbp:postTranslationalModification
|
phosphorylation
|
|
gptkbp:RefSeq
|
NM_004643
|
|
gptkbp:subcellularLocation
|
nucleoplasm
|
|
gptkbp:UniProtID
|
Q86U42
|
|
gptkbp:bfsParent
|
gptkb:Reactome:R-HSA-195721
gptkb:CELF1
gptkb:PABP_proteins
gptkb:poly(A)-binding_proteins
|
|
gptkbp:bfsLayer
|
8
|