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gptkbp:instanceOf
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gptkb:protein
|
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gptkbp:alternativeName
|
Adenosine deaminase acting on RNA 1
Double-stranded RNA-specific adenosine deaminase
|
|
gptkbp:associatedWith
|
Aicardi-Goutieres syndrome
dyschromatosis symmetrica hereditaria
|
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gptkbp:biologicalProcess
|
RNA binding
hydrolase activity
|
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gptkbp:cellularComponent
|
gptkb:nucleus
gptkb:cytoplasm
|
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gptkbp:domain
|
deaminase domain
dsRNA binding domain
|
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gptkbp:encodedBy
|
ADAR gene
|
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gptkbp:Entrez_Gene_ID
|
103
ENSG00000160710
|
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gptkbp:enzymeClassification
|
EC 3.5.4.37
|
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gptkbp:expressedIn
|
ubiquitous
|
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gptkbp:function
|
RNA editing
A-to-I RNA editing
|
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gptkbp:GO
|
GO:0003723
GO:0003968
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gptkbp:hasIsoform
|
gptkb:p110
p150
|
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gptkbp:HGNC_ID
|
HGNC:186
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P78563 (ADAR1)
|
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gptkbp:interactsWith
|
gptkb:STAT1
gptkb:MDA5
NLRP3
DHX9
EIF2AK2
ILF3
|
|
gptkbp:involvedIn
|
innate immune response
interferon response
|
|
gptkbp:length
|
1226 amino acids
|
|
gptkbp:locatedOnChromosome
|
1q21
|
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gptkbp:molecularWeight
|
138 kDa
|
|
gptkbp:OMIM
|
146920
|
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gptkbp:organism
|
gptkb:Homo_sapiens
|
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gptkbp:orthologIn
|
Adar1 (mouse)
|
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gptkbp:PDB
|
5ED1
5HP2
|
|
gptkbp:postTranslationalModification
|
phosphorylation
sumoylation
|
|
gptkbp:RefSeq
|
NP_001102
|
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gptkbp:reviewedBy
|
gptkb:UniProtKB/Swiss-Prot
|
|
gptkbp:subunit
|
homodimer
heterodimer
|
|
gptkbp:UniProtID
|
P78563
|
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gptkbp:bfsParent
|
gptkb:Adenosine_deaminase_acting_on_RNA
|
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gptkbp:bfsLayer
|
7
|