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gptkbp:instanceOf
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UniProt accession number
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gptkbp:alternativeName
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gptkb:Calgranulin-A
gptkb:Migration_inhibitory_factor-related_protein_8
MRP8
Cystic fibrosis antigen
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gptkbp:associatedWith
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inflammatory diseases
cystic fibrosis
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gptkbp:biologicalProcess
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inflammatory response
calcium ion binding
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gptkbp:cellularComponent
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gptkb:cytoplasm
extracellular space
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gptkbp:citation
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Reactome:R-HSA-6798695
GeneCards:S100A8
KEGG:hsa:6279
NCBI Gene:6279
OMIM:123870
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gptkbp:EnsemblGene
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ENSG00000143546
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gptkbp:function
|
antimicrobial activity
regulates inflammatory processes and immune response
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gptkbp:gene
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gptkb:S100A8
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gptkbp:HGNC_ID
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HGNC:10498
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https://www.w3.org/2000/01/rdf-schema#label
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P45452
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gptkbp:locatedOnChromosome
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gptkb:chromosome_1q21
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gptkbp:mass
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10,835 Da
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gptkbp:organism
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gptkb:Homo_sapiens
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gptkbp:PDB
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1M4V
1MR8
4GGF
5I8N
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gptkbp:postTranslationalModification
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gptkb:N-terminal_acetylation
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gptkbp:protein_name
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gptkb:Protein_S100-A8
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gptkbp:refersTo
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Human protein: S100A8
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gptkbp:RefSeq
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NP_002956.1
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gptkbp:reviewedBy
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yes
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gptkbp:sequence
|
93 amino acids
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gptkbp:sequenceStatus
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complete
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gptkbp:subunit
|
homodimer
heterodimer with S100A9
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gptkbp:tissue_specificity
|
expressed in monocytes
expressed in neutrophils
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gptkbp:UniProtEntry
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S10A8_HUMAN
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gptkbp:bfsParent
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gptkb:MMP13
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gptkbp:bfsLayer
|
7
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