|
gptkbp:instanceOf
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gptkb:protein
|
|
gptkbp:alternativeName
|
ATP-gated purinergic receptor P2X7
P2X7 receptor
|
|
gptkbp:associatedWith
|
autoimmune diseases
chronic pain
neuroinflammation
|
|
gptkbp:binds
|
gptkb:ATP
|
|
gptkbp:biologicalProcess
|
ATP binding
inflammatory response
cell death
ion channel activity
regulation of cytokine production
|
|
gptkbp:domain
|
extracellular domain
transmembrane domain
cytoplasmic domain
|
|
gptkbp:encodedBy
|
P2RX7 gene
|
|
gptkbp:Entrez_Gene_ID
|
5027
|
|
gptkbp:expressedIn
|
gptkb:microglia
macrophages
lymphocytes
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:function
|
gptkb:voltage-gated_potassium_channel
|
|
gptkbp:HGNC_ID
|
gptkb:P2RX7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P2X purinoceptor 7
|
|
gptkbp:involvedIn
|
apoptosis
inflammation
immune response
|
|
gptkbp:locatedOnChromosome
|
12q24
|
|
gptkbp:location
|
gptkb:plasma_membrane
|
|
gptkbp:modulatedBy
|
antagonists
agonists
|
|
gptkbp:OMIM
|
602566
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:reactomeID
|
R-HSA-418594
|
|
gptkbp:structure
|
trimeric protein
|
|
gptkbp:subunit
|
gptkb:P2X_receptor_family
|
|
gptkbp:UniProtID
|
Q99572
|
|
gptkbp:bfsParent
|
gptkb:P2RX7
|
|
gptkbp:bfsLayer
|
7
|