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gptkbp:instanceOf
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UniProt accession number
|
|
gptkbp:alternativeName
|
gptkb:CAGA
gptkb:Calgranulin-A
gptkb:Migration_inhibitory_factor-related_protein_8
|
|
gptkbp:amendedBy
|
gptkb:N-terminal_acetylation
|
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gptkbp:associatedWith
|
Inflammatory diseases
|
|
gptkbp:calciumBinding
|
Yes
|
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gptkbp:citation
|
Ensembl: ENSG00000143546
GeneID: 6279
HGNC: 10498
PDB: 1MR8
PDB: 1XK4
PDB: 4GGF
Reactome: R-HSA-6798695
OMIM: 123885
|
|
gptkbp:disulfideBond
|
Yes
|
|
gptkbp:expressedIn
|
Expressed in monocytes
Highly expressed in neutrophils
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gptkbp:function
|
Involved in the regulation of inflammatory processes and immune response
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gptkbp:gene
|
gptkb:S100A8
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P21964
|
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gptkbp:lastAnnotationUpdate
|
2022-02-23
|
|
gptkbp:latestReleaseVersion
|
2007-01-23
|
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gptkbp:length
|
93 amino acids
|
|
gptkbp:locatedOnChromosome
|
1q21
|
|
gptkbp:molecularWeight
|
10,835 Da
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
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gptkbp:organismTaxonomyID
|
9606
|
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gptkbp:pathway
|
Innate Immune System
Neutrophil degranulation
|
|
gptkbp:protein_name
|
gptkb:Protein_S100-A8
|
|
gptkbp:refersTo
|
Human protein S100A8
|
|
gptkbp:reviewedBy
|
Yes (Swiss-Prot)
|
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gptkbp:sequenceStatus
|
Complete
|
|
gptkbp:sequenceVersion
|
Version 2
|
|
gptkbp:structure
|
Homodimer
Heterodimer with S100A9
|
|
gptkbp:subcellularLocation
|
gptkb:Cytoplasm
Secreted
|
|
gptkbp:zincBinding
|
Yes
|
|
gptkbp:bfsParent
|
gptkb:catechol-O-methyl_transferase
|
|
gptkbp:bfsLayer
|
7
|