|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
GST class-pi
GST3
Glutathione S-transferase pi 1
Ligandin
|
|
gptkbp:amendedBy
|
Phosphorylation
S-nitrosylation
N-acetylation
|
|
gptkbp:associatedWith
|
gptkb:cancer
Drug resistance
|
|
gptkbp:ensembl
|
ENSG00000134242
|
|
gptkbp:Entrez_Gene_ID
|
2950
|
|
gptkbp:enzymeClassification
|
EC 2.5.1.18
|
|
gptkbp:family
|
Glutathione S-transferase family
|
|
gptkbp:function
|
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles
|
|
gptkbp:gene
|
GSTP1
|
|
gptkbp:geneOntologyBiologicalProcess
|
cellular detoxification
|
|
gptkbp:geneOntologyCellularComponent
|
cytosol
|
|
gptkbp:geneOntologyMolecularFunction
|
glutathione transferase activity
|
|
gptkbp:hasPolymorphism
|
Ala114Val
Ile105Val
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P09261
|
|
gptkbp:interpro
|
IPR004045
|
|
gptkbp:isoelectricPoint
|
5.4
|
|
gptkbp:literatureReference
|
PMID:15489334
PMID:19332538
PMID:20018852
|
|
gptkbp:locatedOnChromosome
|
gptkb:11q13
|
|
gptkbp:molecularWeight
|
23,226 Da
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:organismTaxonId
|
9606
|
|
gptkbp:pathway
|
Detoxification
Glutathione metabolism
|
|
gptkbp:PDB
|
1GLQ
1GSS
5GST
6GSS
|
|
gptkbp:pfam
|
PF00043
|
|
gptkbp:protein_name
|
Glutathione S-transferase P
|
|
gptkbp:RefSeq
|
NP_000843.1
|
|
gptkbp:sequence
|
210
|
|
gptkbp:subcellularLocation
|
gptkb:Cytoplasm
|
|
gptkbp:subunit
|
Homodimer
|
|
gptkbp:tissue_specificity
|
Expressed in many tissues, highest in placenta, lung, and erythrocytes
|
|
gptkbp:UniProtID
|
gptkb:P09261
|
|
gptkbp:uniprotReviewed
|
Yes
|
|
gptkbp:bfsParent
|
gptkb:Varicella_zoster_virus
|
|
gptkbp:bfsLayer
|
7
|