P03923 (human)

GPTKB entity

Statements (36)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName gptkb:72_kDa_type_IV_collagenase
Gelatinase A
Type IV collagenase
gptkbp:associatedWith gptkb:cardiovascular_disease
Arthritis
Cancer metastasis
gptkbp:cofactor gptkb:Calcium
Zinc
gptkbp:enzymeCommissionNumber 3.4.24.24
gptkbp:function Degrades type IV collagen
Involved in angiogenesis
Involved in tissue remodeling
gptkbp:gene gptkb:MMP2
gptkbp:gene_location_(genomic) gptkb:16q12.2
https://www.w3.org/2000/01/rdf-schema#label P03923 (human)
gptkbp:length 660
gptkbp:locatedOnChromosome 16
gptkbp:molecularWeight 73 kDa
gptkbp:organism gptkb:Homo_sapiens
gptkbp:pathway Cell migration
ECM degradation
gptkbp:PDB 1CK7
1EAK
1GXD
1QIB
gptkbp:postTranslationalModification Phosphorylation
Glycosylation
gptkbp:protein_name Matrix metalloproteinase-2
gptkbp:structure Contains fibronectin type-II domains
Contains hemopexin-like domain
gptkbp:subcellularLocation gptkb:Extracellular_matrix
Secreted
gptkbp:UniProtID P03923
gptkbp:bfsParent gptkb:ND6
gptkbp:bfsLayer 7