gptkbp:instanceOf
|
gptkb:protein
|
gptkbp:alternativeName
|
gptkb:72_kDa_type_IV_collagenase
Gelatinase A
Type IV collagenase
|
gptkbp:associatedWith
|
gptkb:cardiovascular_disease
Arthritis
Cancer metastasis
|
gptkbp:cofactor
|
gptkb:Calcium
Zinc
|
gptkbp:enzymeCommissionNumber
|
3.4.24.24
|
gptkbp:function
|
Degrades type IV collagen
Involved in angiogenesis
Involved in tissue remodeling
|
gptkbp:gene
|
gptkb:MMP2
|
gptkbp:gene_location_(genomic)
|
gptkb:16q12.2
|
https://www.w3.org/2000/01/rdf-schema#label
|
P03923 (human)
|
gptkbp:length
|
660
|
gptkbp:locatedOnChromosome
|
16
|
gptkbp:molecularWeight
|
73 kDa
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
gptkbp:pathway
|
Cell migration
ECM degradation
|
gptkbp:PDB
|
1CK7
1EAK
1GXD
1QIB
|
gptkbp:postTranslationalModification
|
Phosphorylation
Glycosylation
|
gptkbp:protein_name
|
Matrix metalloproteinase-2
|
gptkbp:structure
|
Contains fibronectin type-II domains
Contains hemopexin-like domain
|
gptkbp:subcellularLocation
|
gptkb:Extracellular_matrix
Secreted
|
gptkbp:UniProtID
|
P03923
|
gptkbp:bfsParent
|
gptkb:ND6
|
gptkbp:bfsLayer
|
7
|