Statements (111)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
CA-I
Carbonate dehydratase I Carbonic anhydrase I |
| gptkbp:associatedWith |
gptkb:hereditary_elliptocytosis
|
| gptkbp:biologicalProcess |
catalyzes the reversible hydration of carbon dioxide
|
| gptkbp:cellularComponent |
gptkb:cytoplasm
|
| gptkbp:citation |
ChEMBL: CHEMBL2094112
Ensembl: ENSG00000133742 GeneID: 759 HGNC: 1374 KEGG: hsa:759 OMIM: 114800 Reactome: R-HSA-1475029 |
| gptkbp:cofactor |
Zinc
|
| gptkbp:enzymeCommissionNumber |
4.2.1.1
|
| gptkbp:function |
regulation of pH and CO2 transport
|
| gptkbp:gene |
CA1
|
| gptkbp:has3DStructure |
Yes
|
| gptkbp:hasIsoform |
1
|
| https://www.w3.org/2000/01/rdf-schema#label |
P00909
|
| gptkbp:locatedOnChromosome |
8
8q21.2 |
| gptkbp:mass |
28,851 Da
|
| gptkbp:organism |
gptkb:Homo_sapiens
9606 |
| gptkbp:pathway |
bicarbonate transport
|
| gptkbp:PDB |
gptkb:1CA2
gptkb:3HS4 gptkb:1AZM 1CRM 1CZM 1QRG 2CAB 3HS5 3HS6 3HS7 3HS8 3HS9 3HSA 3HSB 3HSC 3HSD 3HSE 3HSF 3HSG 3HSH 3HSI 3HSJ 3HSK 3HSL 3HSM 3HSN 3HSO 3HSP 3HSQ 3HSR 3HSS 3HST 3HSU 3HSV 3HSW 3HSX 3HSY 3HSZ 4HS1 4HS2 4HS3 4HS4 4HS5 4HS6 4HS7 4HS8 4HS9 4HSA 4HSB 4HSC 4HSD 4HSE 4HSF 4HSG 4HSH 4HSI 4HSJ 4HSK 4HSL 4HSM 4HSN 4HSO 4HSP 4HSQ 4HSR 4HSS 4HST 4HSU 4HSV 4HSW 4HSX 4HSY 4HSZ |
| gptkbp:postTranslationalModification |
phosphorylation
acetylation |
| gptkbp:proteinFamily |
gptkb:carbonic_anhydrase_family
|
| gptkbp:recommendation |
gptkb:Carbonic_anhydrase_1
|
| gptkbp:sequence |
261
|
| gptkbp:subcellularLocation |
gptkb:cytoplasm
|
| gptkbp:subunit |
monomer
|
| gptkbp:tissue_specificity |
erythrocytes
|
| gptkbp:UniProtID |
gptkb:P00909
|
| gptkbp:bfsParent |
gptkb:tryptophanase
|
| gptkbp:bfsLayer |
8
|