|
gptkbp:instanceOf
|
gptkb:enzyme
|
|
gptkbp:alternativeName
|
Carbonate dehydratase I
CA I
|
|
gptkbp:associatedWith
|
carbonic anhydrase deficiency syndrome
|
|
gptkbp:cofactor
|
zinc
|
|
gptkbp:EC_number
|
4.2.1.1
|
|
gptkbp:Entrez_Gene_ID
|
759
ENSG00000133742
|
|
gptkbp:expressedIn
|
red blood cells
|
|
gptkbp:family
|
gptkb:carbonic_anhydrase_family
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:function
|
catalyzes reversible hydration of carbon dioxide
|
|
gptkbp:gene
|
CA1
|
|
gptkbp:inhibitedBy
|
gptkb:acetazolamide
sulfonamides
|
|
gptkbp:locatedIn
|
erythrocytes
|
|
gptkbp:locatedOnChromosome
|
8q21.2
|
|
gptkbp:molecularWeight
|
28 kDa
|
|
gptkbp:OMIM
|
114800
|
|
gptkbp:PDB
|
gptkb:1AZM
|
|
gptkbp:product
|
gptkb:proton
bicarbonate
|
|
gptkbp:RefSeq
|
NP_001729.1
|
|
gptkbp:role
|
CO2 transport
respiratory gas exchange
regulation of pH
|
|
gptkbp:structure
|
monomeric protein
|
|
gptkbp:substrate
|
carbon dioxide
|
|
gptkbp:tissue_specificity
|
high in erythrocytes
low in other tissues
|
|
gptkbp:UniProtID
|
gptkb:P00915
|
|
gptkbp:bfsParent
|
gptkb:CA-1
|
|
gptkbp:bfsLayer
|
8
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Carbonic anhydrase 1
|