|
gptkbp:instanceOf
|
UniProt accession number
|
|
gptkbp:activeSiteResidue
|
Asp-107
His-63
Ser-200
|
|
gptkbp:alternativeName
|
Cationic trypsinogen
Serine protease 1
|
|
gptkbp:associatedWith
|
Hereditary pancreatitis
|
|
gptkbp:catalyzes
|
Hydrolysis of peptide bonds
|
|
gptkbp:cofactor
|
gptkb:Calcium
|
|
gptkbp:disulfideBond
|
42-58
136-201
165-181
|
|
gptkbp:domain
|
Trypsin-like serine protease domain
|
|
gptkbp:EC_number
|
3.4.21.4
|
|
gptkbp:Entrez_Gene_ID
|
5644
ENSG00000172023
|
|
gptkbp:family
|
Peptidase S1 family
|
|
gptkbp:function
|
Serine protease involved in digestion
|
|
gptkbp:gene
|
gptkb:PRSS1
|
|
gptkbp:glycosylation
|
Asn-90
|
|
gptkbp:hasIsoform
|
1
|
|
gptkbp:hasPolymorphism
|
Associated with pancreatitis
|
|
gptkbp:HGNC_ID
|
9477
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P00760
|
|
gptkbp:lastAnnotationUpdate
|
2021-10-13
|
|
gptkbp:latestReleaseVersion
|
1992-10-01
|
|
gptkbp:locatedOnChromosome
|
gptkb:7q34
|
|
gptkbp:massSpectrometry
|
Detected
|
|
gptkbp:molecularWeight
|
26398 Da
|
|
gptkbp:name
|
TRY1_HUMAN
|
|
gptkbp:OMIM
|
276000
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:PDB
|
gptkb:1TRN
2PTN
3TGI
|
|
gptkbp:postTranslationalModification
|
Activation peptide cleavage
|
|
gptkbp:protein_name
|
Trypsin-1
|
|
gptkbp:refersTo
|
Trypsin-1
|
|
gptkbp:sequence
|
247
MDSK... (full sequence available in UniProt)
|
|
gptkbp:sequenceVersion
|
2
|
|
gptkbp:signalPeptide
|
1-15
|
|
gptkbp:status
|
Reviewed
|
|
gptkbp:subcellularLocation
|
Secreted
|
|
gptkbp:tissue_specificity
|
Pancreas
|
|
gptkbp:UniGene
|
Hs.654
|
|
gptkbp:bfsParent
|
gptkb:trypsin
|
|
gptkbp:bfsLayer
|
6
|