Statements (28)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:gene
|
gptkbp:alias |
cationic trypsinogen
trypsinogen 1 |
gptkbp:associatedWith |
pancreatitis
hereditary pancreatitis |
gptkbp:biologicalProcess |
digestion
endopeptidase activity |
gptkbp:encodes |
trypsin-1
|
gptkbp:Entrez_Gene_ID |
5644
ENSG00000172023 |
gptkbp:expressedIn |
pancreas
|
gptkbp:function |
serine protease activity
digestion of proteins |
gptkbp:HGNC_ID |
9477
|
https://www.w3.org/2000/01/rdf-schema#label |
PRSS1
|
gptkbp:locatedOnChromosome |
gptkb:7q34
gptkb:chromosome_7 |
gptkbp:mutationAssociatedWith |
increased trypsin activity
autodigestion of pancreas |
gptkbp:OMIM |
276000
|
gptkbp:orthologInMouse |
Prss1
|
gptkbp:pathway |
pancreatic secretion
protein digestion and absorption |
gptkbp:product |
cationic trypsinogen
|
gptkbp:proteinFamily |
serine protease family
|
gptkbp:UniProtID |
P07477
|
gptkbp:bfsParent |
gptkb:trypsin
|
gptkbp:bfsLayer |
6
|