PRSS1

GPTKB entity

Statements (28)
Predicate Object
gptkbp:instanceOf gptkb:gene
gptkbp:alias cationic trypsinogen
trypsinogen 1
gptkbp:associatedWith pancreatitis
hereditary pancreatitis
gptkbp:biologicalProcess digestion
endopeptidase activity
gptkbp:encodes trypsin-1
gptkbp:Entrez_Gene_ID 5644
ENSG00000172023
gptkbp:expressedIn pancreas
gptkbp:function serine protease activity
digestion of proteins
gptkbp:HGNC_ID 9477
https://www.w3.org/2000/01/rdf-schema#label PRSS1
gptkbp:locatedOnChromosome gptkb:7q34
gptkb:chromosome_7
gptkbp:mutationAssociatedWith increased trypsin activity
autodigestion of pancreas
gptkbp:OMIM 276000
gptkbp:orthologInMouse Prss1
gptkbp:pathway pancreatic secretion
protein digestion and absorption
gptkbp:product cationic trypsinogen
gptkbp:proteinFamily serine protease family
gptkbp:UniProtID P07477
gptkbp:bfsParent gptkb:trypsin
gptkbp:bfsLayer 6