Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
solute carrier protein |
| gptkbp:alternativeName |
gptkb:SLC22A5
Organic cation/carnitine transporter 2 |
| gptkbp:encodedBy |
gptkb:SLC22A5_gene
|
| gptkbp:expressedIn |
gptkb:skeletal_muscle
gptkb:kidney heart liver |
| gptkbp:function |
transports carnitine
transports organic cations |
| https://www.w3.org/2000/01/rdf-schema#label |
OCTN2 transporter
|
| gptkbp:inhibitedBy |
gptkb:prazosin
gptkb:verapamil quinidine |
| gptkbp:locatedOnChromosome |
5q31
|
| gptkbp:location |
gptkb:plasma_membrane
|
| gptkbp:mutationAssociatedWith |
gptkb:primary_carnitine_deficiency
gptkb:systemic_carnitine_deficiency |
| gptkbp:significance |
drug interactions
carnitine uptake in tissues |
| gptkbp:species |
gptkb:Mus_musculus
gptkb:Homo_sapiens |
| gptkbp:structure |
12 transmembrane domains
|
| gptkbp:substrate |
gptkb:carnitine
gptkb:acetylcarnitine organic cations |
| gptkbp:transporterFamily |
gptkb:SLC22_family
|
| gptkbp:UniProtID |
O76082
|
| gptkbp:bfsParent |
gptkb:OCTN2
|
| gptkbp:bfsLayer |
7
|