|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alsoKnownAs
|
gptkb:SLC22A4
|
|
gptkbp:associatedWith
|
gptkb:Crohn's_disease
inflammatory bowel disease
|
|
gptkbp:expressedIn
|
gptkb:kidney
heart
liver
intestine
|
|
gptkbp:family
|
gptkb:SLC22_family
|
|
gptkbp:function
|
organic cation transporter
|
|
gptkbp:gene
|
gptkb:SLC22A4_gene
|
|
gptkbp:HGNC_ID
|
10941
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
OCTN1 transporter
|
|
gptkbp:locatedIn
|
gptkb:cell_membrane
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_5q31
|
|
gptkbp:memberOf
|
gptkb:solute_carrier_family
|
|
gptkbp:molecularWeight
|
approximately 61 kDa
|
|
gptkbp:mutationAssociatedWith
|
altered substrate specificity
|
|
gptkbp:OMIM
|
604190
|
|
gptkbp:orthologIn
|
gptkb:mouse
right
|
|
gptkbp:regulates
|
transcriptional and post-translational
|
|
gptkbp:significance
|
pharmacokinetics of drugs
|
|
gptkbp:species
|
gptkb:Homo_sapiens
|
|
gptkbp:structure
|
12 transmembrane domains
|
|
gptkbp:substrate
|
gptkb:broadcaster
|
|
gptkbp:transportation
|
gptkb:carnitine
gptkb:ergothioneine
gptkb:tetraethylammonium
|
|
gptkbp:UniProtID
|
O76082
|
|
gptkbp:bfsParent
|
gptkb:ergothioneine
|
|
gptkbp:bfsLayer
|
8
|