|
gptkbp:instance_of
|
gptkb:drug
|
|
gptkbp:bfsLayer
|
5
|
|
gptkbp:bfsParent
|
gptkb:esomeprazole
|
|
gptkbp:approves
|
gptkb:2001
|
|
gptkbp:availability
|
Prescription only
|
|
gptkbp:brand
|
gptkb:Nexium
|
|
gptkbp:class
|
Proton pump inhibitor
|
|
gptkbp:clinical_trial
|
Phase IV
> 50%
|
|
gptkbp:code
|
A02 B C05
|
|
gptkbp:contraindication
|
Severe liver impairment
Hypersensitivity to esomeprazole
|
|
gptkbp:dosage_form
|
IV infusion
|
|
gptkbp:duration
|
Varies by condition
|
|
gptkbp:excretion
|
Urine
|
|
gptkbp:formulation
|
Injection
|
|
gptkbp:frequency
|
Once daily
|
|
gptkbp:healthcare
|
gptkb:battle
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Nexium IV
|
|
gptkbp:indication
|
Prevention of gastric ulcers
Treatment of H. pylori infection
|
|
gptkbp:ingredients
|
gptkb:Esomeprazole
|
|
gptkbp:interacts_with
|
gptkb:Clopidogrel
gptkb:Methotrexate
gptkb:Digoxin
gptkb:Warfarin
|
|
gptkbp:is_used_for
|
gptkb:Zollinger-Ellison_syndrome
Gastroesophageal reflux disease (GERD)
Erosive esophagitis
|
|
gptkbp:lifespan
|
~ 1.3 hours
|
|
gptkbp:manager
|
Intravenous
|
|
gptkbp:manufacturer
|
gptkb:temple
|
|
gptkbp:marketed_as
|
gptkb:Nexium
|
|
gptkbp:metabolism
|
Liver
|
|
gptkbp:packaging
|
Vial
|
|
gptkbp:population
|
Adults
Pediatric patients
|
|
gptkbp:price
|
Varies by region
|
|
gptkbp:requires
|
Available
|
|
gptkbp:shelf_life
|
24 months
|
|
gptkbp:side_effect
|
gptkb:Nausea
Diarrhea
Headache
Constipation
Abdominal pain
|
|
gptkbp:social_structure
|
C17 H18 N3 O3 S
|
|
gptkbp:storage
|
Room temperature
|