Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:N-cadherin
|
| gptkbp:discoveredIn |
1980s
|
| gptkbp:encodedBy |
gptkb:CDH2_gene
|
| gptkbp:expressedIn |
gptkb:skeletal_muscle
cardiac muscle neurons lens of the eye |
| gptkbp:foundIn |
humans
mammals |
| gptkbp:function |
neural development
cell adhesion synapse formation |
| gptkbp:gene |
gptkb:CDH2
|
| https://www.w3.org/2000/01/rdf-schema#label |
Neural cadherin
|
| gptkbp:interactsWith |
gptkb:alpha-catenin
gptkb:p120-catenin gptkb:beta-catenin |
| gptkbp:locatedOnChromosome |
gptkb:18q12.1
|
| gptkbp:location |
gptkb:plasma_membrane
|
| gptkbp:molecularWeight |
~130 kDa
|
| gptkbp:mutationAssociatedWith |
gptkb:autism_spectrum_disorder
bipolar disorder schizophrenia congenital heart defects neurodevelopmental disorders |
| gptkbp:role |
embryonic development
epithelial-mesenchymal transition cancer metastasis |
| gptkbp:structure |
transmembrane protein
|
| gptkbp:superfamily |
gptkb:cadherin_superfamily
|
| gptkbp:bfsParent |
gptkb:CDH2
|
| gptkbp:bfsLayer |
7
|