Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:cofactor |
gptkb:FMN
gptkb:FAD gptkb:tetrahydrobiopterin NADPH |
| gptkbp:EC_number |
1.14.13.39
|
| gptkbp:foundIn |
gptkb:Bacteria
animals |
| gptkbp:fullName |
nitric oxide synthase
|
| gptkbp:function |
catalyzes the production of nitric oxide from L-arginine
|
| gptkbp:gene |
NOS3
NOS1 NOS2 |
| gptkbp:hasIsoform |
endothelial nitric oxide synthase (eNOS)
inducible nitric oxide synthase (iNOS) neuronal nitric oxide synthase (nNOS) |
| https://www.w3.org/2000/01/rdf-schema#label |
NO synthase
|
| gptkbp:inhibitedBy |
gptkb:L-NAME
gptkb:aminoguanidine |
| gptkbp:product |
nitric oxide
L-citrulline |
| gptkbp:requires |
oxygen
NADPH |
| gptkbp:role |
cell signaling
immune response vasodilation |
| gptkbp:structure |
homodimer
|
| gptkbp:substrate |
gptkb:L-arginine
|
| gptkbp:bfsParent |
gptkb:Nitric_oxide_synthase
|
| gptkbp:bfsLayer |
7
|